Major achievements in BIOCOM

Biogenic amines in seafoods - assessment and management of consumer exposure

Major achievements in 2004

There has been a high level of activity within the project. Eight outbreaks of histamine poisoning were investigated in the first 10 months. The high level of activity means it is now proposed that required data from the initial phase of the work will be gathered within 24 rather than 36 months. It has been well documented that seafood containing levels of histamine above 500-1000 mg/kg has been responsible for histamine fish poisoning (HFP). Formation of these toxic concentrations of histamine and other biogenic amines is typically considered to result from the growth and activity of mesophilic enterobacteria where seafood is stored at temperatures, above 7-10C. The BIOCOM project has identified psychrotolerant Morganella morganii-like bacteria and Photobacterium phosphoreum, growing at temperatures as low as 2C, as being responsible for histamine formation in cold-smoked tuna that caused HFP. This is a significant breakthrough in our understanding of the causes for histamine poisoning, and forms the basis for new strategies to avoid HFP in future.

See News items

Kick off meeting BIOCOM and rapid research news about histamine fish poisoning 16-01-04


The kick off meeting of the project 3.4 Biogenic amines in seafoods - assessment and management of consumer exposure (BIOCOM) in RTD Pillar 3 Seafdood safety was held on 16 January 2004 and less than two week later an outbreak of histamine fish poisoning occurred in Denmark.

Luminous bacteria in first outbreak of histamine poisoning analysed in SEAFOODplus project 3.4. BIOCOM 16-01-04


End of January an outbreak of histamine fish poisoning occurred in Denmark. The project team of SEAFOODplus project 3.4. BIOCOM obtained samples of the implicated seafood and analyses showed the product to contain luminous bacteria.

Projectleader BIOCOM

Dr. Paw Dalgaard

DTU Aqua, Denmark